Mario Capecchi's Publications:

Capecchi, M. R. and G. N. Gussin (1965). Suppression in vitro:  Identification of a serine-tRNA as a "Nonsense Suppressor." Science149:417-422.

Adams, J. M. and M. R. Capecchi (1966). N-formylmethionine-tRNA as the initiator of protein syntheses. Proc. Natl. Acad. Sci. USA55:147-155.

Capecchi, M. R. (1966). Initiation of E. coli proteins. Proc. Natl. Acad. Sci. USA55:1517-1524.

Capecchi, M. R. (1966). Cell-free protein synthesis programmed with R17 RNA:  Identification of two phage proteins. J. Mol. Biol. 21:173-193.

Bergquist, P. L. and M. R. Capecchi (1966). Fractionation of a suppressor tRNA. J. Mol. Biol.19:202-206.

Gussin, G. N., M. R. Capecchi, J. M. Adams, J. E. Argetsinger, J. Tooze, K. Weber and J. D. Watson (1966).  Protein synthesis directed by RNA phage messengers.  Cold Spring Harbor Symp. Quant. Biol. 31:257-271.

Capecchi, M. R. (1967). Polycistronic messenger RNA and the phenomenon of suppression, BBA Library.  In Regulation of Nucleic Acid and Protein Synthesis (V. V. Konigsberger and L. Bosch, Ed.), Vol. 10, pp. 243-258.  Amsterdam:  Elsevier Publishing Co.

Capecchi, M. R. (1967). A rapid assay for polypeptide chain termination. Biophys. Res. Comm. 28:773-778.

Capecchi, M. R. (1967). Polypeptide chain termination in vitro:  Isolation of a release factor. Proc. Natl. Acad. Sci. USA58:1144-1151.

Capecchi, M. R. (1967). Polarity in vitro. J. Mol. Biol. 30:213-217.

Capecchi, M. R. and H. A. Klein (1969). Characterization of three proteins involved in polypeptide chain termination. Cold Spring Harbor Symp. Quant. Biol. 28:469-477.

Capecchi, M. R. and H. A. Klein (1970). Release factors mediating termination of complete proteins. Nature26:1029-1033.

Klein, H. A. and M. R. Capecchi (1971). Polypeptide chain termination, purification of the release factors, R1 and  R2 from Escherichia coli. J. Biol. Chem. 246:1055-1061.

Sharp, J. D., N. E. Capecchi and M. R. Capecchi (1973). Altered enzymes in drug resistant variants of mammalian tissue culture cells. Proc. Natl. Acad. Sci. USA70:4732-4736.

Capecchi, M. R., N. E. Capecchi, S. H. Hughes and G. M. Wahl (1974). Selective degradation of abnormal proteins in mammalian tissue culture cells. Proc. Natl. Acad. Sci. USA71:4732-4736.

Hughes, S. H., G. M. Wahl and M. R. Capecchi (1975). Purification and characterization of mouse hypoxanthine-guanine phosphoribosyl transferase. J. Biol. Chem. 250:120-126.

Wahl, G. M., S. H. Hughes and M. R. Capecchi (1975). Immunological characterization of hypoxanthine-guanine phosphoribosyl transferase mutants of mouse L cells: Evidence for mutations at different loci n the HGPRT gene. J. Cell Phys. 85:307-320.

Capecchi, M. R., S. H. Hughes and G. M. Wahl (1975). Yeast super suppressors are altered tRNAs capable of translating a nonsense codon in vitro. Cell6:269-277.

Capecchi, M. R. and R. E. Webster (1975). Bacteriophage RNA as template for in vitro protein synthesis.  In RNA Phages (N. D. Zinder, Ed.).  Pp. 279-299.  Cold Spring Harbor, New York:  Cold Spring Harbor Press.

Capecchi, M. R., R. A. V. Haar, N. E. Capecchi and M. M. Sveda (1977). The isolation of a suppressible nonsense mutant in mammalian cells. Cell12:371-381.

Capecchi, M. R., R. A. V. Haar, N. E. Capecchi and M. M. Sveda (1977). Molecular approaches to eucaryotic genetic systems. ICN-UCLA Symposia8:381-398.

Capecchi, M. R., R. A. V. Haar and M. M. Sveda (1978). Characterization of nonsense mutants in mammalian cells in culture.  In Mutations and tRNA Nonsense Suppressors (J. E. Celis and J. D. Smith, Eds.).  New York:  Academic Press.  

Capecchi, M. R. (1980). High efficiency transformation by direct microinjection of DNA into cultured mammalian cells. Cell22:479-488.

Folger, K. R., E. A. Wong, G. Wahl and M. R. Capecchi (1982). Patterns of integration of DNA microinjected into cultured mammalian cells:  Evidence for homologous recombination between injected plasmid DNA molecules. Mol. Cell. Biol. 2:1372-1387.

Hudziak, R. M., F. A. Laski, U. L. R. Bhandary, P. A. Sharp and M. R. Capecchi (1982). Establishment of mammalian cell lines containing multiple nonsense mutations and functional suppressor tRNA genes. Cell31:137-146.           

Luciw, P. A., J. M. Bishop, H. E. Varmus and M. R. Capecchi (1983). Location and function of retroviral and SV40 sequences that enhance biochemical transformation after microinjection of DNA. Cell33:705-716.

Young, J. F., M. R. Capecchi, F. A. Laski, U. L. R. Bhandary, P. A. Sharp and P. Palese (1983). Measurement of suppressor transfer RNA activity. Science221:873-875.

Folger, K. R., K. R. Thomas and M. R. Capecchi (1984). Analysis of homologous recombination in cultured mammalian cells. Cold Spring Harbor Symp. Quant. Biol.49:123-138.

Laski, F. A., R. Belagaje, R. M. Hudziak, M. R. Capecchi, G. P. Norton, P. Palese, U. L. R. Bhandary and P. A. Sharp (1984). Synthesis of an ochre suppressor tRNA gene and expression in mammalian cells. EMBO J. 3:2445-2452.

Folger, K. R., K. R. Thomas and M. R. Capecchi (1985). Nonreciprocal exchanges of information between DNA duplexes coinjected into mammalian cell nuclei. Mol. Cell. Biol. 5:59-69.

Folger, K. R., K. R. Thomas and M. R. Capecchi (1985). Efficient correction of mismatched bases in plasmid heteroduplexes injected into cultured mammalian cell nuclei. Mol. Cell. Biol. 5:70-74.

Frels, W. I., J. A. Bluestone, R. J. Hodes, M. R. Capecchi and D. S. Singer (1985). Expression of a microinjected porcine class I major histocompatibility complex gene in transgenic mice. Science228:577-580.

Wong, E. A. and M. R. Capecchi (1985). Effects of cell cycle position on transformation by microinjection. Somat. Cell Mol. Genet. 11:45-51.

Goddard, J. M., J. J. Weiland and M. R. Capecchi (1986). Isolation and characterization of Caenorhabditis elegans DNA sequences homologous to the V-abl oncogene. Proc. Natl. Acad. Sci. USA83:2172-2176.

Thomas, K. R., K. R. Folger and M. R. Capecchi (1986). High frequency targeting of genes to specific sites in the mammalian genome. Cell44:419-428.

Wong, E. A. and M. R. Capecchi (1986). Analysis of homologous recombination in cultured mammalian cells in a transient expression and a stable transformation assay. Somat. Cell Mol. Genet. 12:63-72.

Thomas, K. R., and M. R. Capecchi (1986). Introduction of homologous DNA sequences into mammalian cells induces mutations in the cognate gene. Nature324:34-38.

Thomas, K. R. and M. R. Capecchi (1986). Targeting of genes to specific sites in the mammalian genome. Cold Spring Harbor Symp. Quant. Biol. 51:1101-1113.

Wong, E. A. and M. R. Capecchi (1987). Homologous recombination between coinjected DNA sequences peaks in early to mid-S phase. Mol. Cell. Biol. 7:2294-2295.

Thomas, K. R. and M. R. Capecchi (1987). Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell 51:503-512.

Mansour, S. L., K. R. Thomas and M. R. Capecchi (1988). Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells:  A general strategy for targeting mutations to nonselectable genes. Nature336:348-352.

Capecchi, M. R. (1989). Altering the genome by homologous recombination. Science244:1288-1292.

Capecchi, M. R., K. R. Thomas and S. L. Mansour (1989). Creating mice with specific mutations by gene targeting. In Molecular Genetics of Early Drosophila and Mouse Development (M. R. Capecchi, Ed.). Pp. 45-52.  Cold Spring Harbor, New York:  Cold Spring Harbor Press.

Capecchi, M. R. (1989). The new mouse genetics:  altering the genome by gene targeting. Trends Genet. 5:70-76.

Mansour, S. L., K. R. Thomas, C. Deng and M. R. Capecchi (1990). Introduction of a lacZ reporter gene into the mouse int-2 locus by homologous recombination.  Proc. Natl. Acad. Sci. USA87:7688-7692.

Thomas, K. R. and M. R. Capecchi (1990). Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development. Nature346:847-850.

Capecchi, M. R. (1990). Tapping the cellular telephone. Nature344:105.

Capecchi, M. R. (1990). How efficient can you get? Nature348:109.

Chisaka, O. and M. R. Capecchi (1991). Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5. Nature350:473-479.

Thomas, K. R., T. A. Musci, P. E. Neumann and M. R. Capecchi (1991). Swaying is a mutant allele of the proto-oncogene Wnt-1. Cell67:969-976.

Chisaka, O., T. S. Musci and M. R. Capecchi (1992). Developmental defects of the ear, cranial nerves and hindbrain resulting from targeted disruption of the mouse homeobox gene hox-1.6. Nature355:516-520.

Deng, C. and M. R. Capecchi (1992). Reexamination of gene targeting frequency as a function of the extent of homology between the targeting vector and the target locus. Mol. Cell. Biol. 12:3365-3371.

Thomas, K. R., C. Deng and M. R. Capecchi (1992). High-fidelity gene targeting in embryonic stem cells by using sequence replacement vectors.  Mol. Cell. Biol. 12:2919-2923.

Mansour, S. L., J. M. Goddard and M. R. Capecchi (1993). Mice homozygous for a targeted disruption of the proto-oncogene int-2 have developmental defects in the tail and inner ear. Development117:13-28.

Deng, C., K. R. Thomas and M. R. Capecchi (1993). Location of crossovers during gene targeting with insertion and replacement vectors. Mol. Cell. Biol. 13:2134-2140.

Capecchi, M. R. (1993). YACs to the rescue. Nature362:205-206.

Carpenter, E. M., J. M. Goddard, O. Chisaka, N. R. Manley and M. R. Capecchi (1993). Loss of Hoxa-1 (Hox-1.6) function results in the reorganization of the murine hindbrain. Development118:1063-1075.

Condie, B. G. and M. R. Capecchi (1993).  Mice homozygous for a targeted disruption of Hoxd-3 (Hox-4.1) exhibit anterior transformations of the first and second cervical vertebrae, the atlas and the axis.  Development 119:579-595.

Capecchi, M. R. (1994).  Targeted gene replacement.  Sci. Am. 270:54-61.

Kostic, D. and M. R. Capecchi (1994).  Targeted disruptions of the murine hoxa-4 and hoxa-6 genes result in homeotic transformations of components of the vertebral column.  Mech. Dev. 46:231-247.

Davis, A. P. and M. R. Capecchi (1994).  Axial homeosis and appendicular skeleton defects in mice with targeted disruption of hoxd-11.  Development120:2187-2198.

Condie, B. G. and M. R. Capecchi (1994).  Mice with targeted disruptions in the paralogous genes hoxa-3 and hoxd-3 reveal synergistic interactions.  Nature370:304-307.

Spyropoulos, D. D. and M. R. Capecchi (1994).  Targeted disruption of the even-skipped gene, evx1, causes early postimplantation lethality of the mouse conceptus.  Genes Dev. 8:1949-1961.

Rancourt, D. E., T. Tsuzuki and M. R. Capecchi (1995).  Genetic interaction betweeen hoxb-5 and hoxb-6 is revealed by nonallelic noncomplementation.  Genes Dev. 9:108-122.

Capecchi, M. R. (1995).  A personal view of gene targeting.  In Accomplishments in Cancer Research 1994.  (J. G. Fortner and J. E. Rhoads, Ed.)  Philadelphia:  J. B. Lippincott, pp. 67-78. 

Manley, N.R. and M.R. Capecchi (1995).  The role of hoxa-3 in mouse thymus and thyroid development.  Development121:1989-2003.

Davis, A.P., D.P. Witte, H.M. Hsieh-Li, S.S. Potter and M.R. Capecchi (1995).  Absence of radius and ulna in mice lacking hoxa-11 and hoxd-11.  Nature375:791-796.

Capecchi, M.R. (1995).  The molecular genetic analysis of mouse development.  In Seminars in Developmental Biology.  (M.R. Capecchi, Ed.)  London: Academic Press 6:233-237.                                                                                                                       

Zeiher, B.G., E. Eichwald, J. Zabner, J.J. Smith, A.P. Puga, P.B. McCray, Jr., M.R. Capecchi, M.J. Welsh, and K.R. Thomas (1995).  A mouse model for the D-F508 allele of cystic fibrosis.  J. Clin. Invest. 96:2051-2064.

Davis, A.P. and M.R. Capecchi (1996).  A mutational analysis of the 5' Hox D genes:  Dissection of genetic interactions during limb development in the mouse.  Development  122:1175-1185.

Delort, J.P. and M.R. Capecchi (1996).  TAXI/UAS:  a molecular switch to control expression of genes in vivo.  Hum. Gene Ther. 7:809-820.    

Boulet, A.M. and M.R. Capecchi (1996).  Targeted disruption of hoxc-4 causes esophageal defects and vertebral transformations.  Dev. Biol. 177:232-249.

Esther, C. R., Jr., T. E. Howard, E. M. Marino, J. M. Goddard, M. R. Capecchi and K. E. Bernstein  (1996).  Mice lacking angiotensin-converting enzyme have low blood pressure, renal pathology, and reduced male fertility.  Lab. Invest. 74:953-965.

Goddard, J. M., M. Rossel, N. R. Manley and M. R. Capecchi  (1996).  Mice with targeted disruption of Hoxb-1 fail to form the motor nucleus of the VIIth nerve.  Development 122:3217-3228.

Barrow, J. R. and M. R. Capecchi (1996).  Targeted disruption of the hoxb-2 locus in mice interferes with expression of hoxb-1 and hoxb-4.  Development122:3817-3828.

Esther, C. R., Jr., T. E. Howard, Y. Zhou, M. R. Capecchi, M. B. Marrero and K. E. Bernstein (1996).  Lessons from angiotensin-converting enzyme-deficient mice.  Curr. Opin. Nephrol. Hypertens. 5:463-467.    

Capecchi, M. R. (1996).  Function of homeobox genes in skeletal development.  In Molecular and Developmental Biology of Cartilage, Vol. 785.  (B. de Crombrugghe, W. A. Horton, B. R. Olsen, and F. Ramirez, Eds.)  Ann. N. Y. Acad. Sci. 785:34-37.

Chen, F. and M. R. Capecchi (1997).  Targeted mutations in Hoxa-9 and Hoxb-9 reveal synergistic interactions.  Dev. Biol. 181:186-196.

Humphries, M. M., D. Rancourt, G. J. Farrar, P. Kenna, M. Hazel, R. A. Bush, P. A. Sieving, D. M. Sheils, N. McNally, P. Creighton, A. Erven, A. Boros, K. Gulya, M. R. Capecchi and P. Humphries (1997).  Retinopathy induced in mice by targeted disruption of the rhodopsin gene.  Nature Genet.15:216-219.

Thomas, K. R. and M. R. Capecchi (1997).  Recombinant DNA technique and sickle cell anemia research.  Science. 275:1404-1405.

Capecchi, M. R. (1997).  The role of Hox genes in hindbrain development.  In Molecular and Cellular Approaches to Neural Development.  (W.M. Cowan, T.M. Jessell and S.L. Zipursky, Eds.)  New York:  Oxford University Press, pp. 334-355.

Esther, C. R., Jr., E. M. Marino, T. E. Howard, A. Machaud, P. Corvol, M. R. Capecchi and K. E. Bernstein (1997).  The critical role of tissue angiotensin-converting enzyme as revealed by gene targeting in mice.  J. Clin. Invest. 99:2375-2385.

Carpenter, E. M., J. M. Goddard, A. P. Davis, T. P. Nguyen and M. R. Capecchi (1997).  Targeted disruption of Hoxd10 affects mouse hindlimb development.  Development 124:4505-4514.

Capecchi, M. R. (1997).  Hox genes and mammalian development.  In Cold Spring Harbor Symposia on Quantitative Biology:  Pattern Formation during Development.  Vol. LXII.  Cold Spring Harbor, NY:  Cold Spring Harbor Laboratory Press, pp. 273-281.

Condie, B. C., G. Bain, D. I. Gottlieb and M. R. Capecchi (1997).  Cleft palate in mice with a targeted mutation in the g-aminobutyric acid-producing enzyme glutamic acid decarboxylase 67. Proc. Natl. Acad. Sci. USA94:11451-11455. 

Manley, N. R. and M. R. Capecchi (1997).  Hox group 3 paralogous genes act synergistically in the formation of somitic and neural crest-derived structures.  Dev. Biol.192:274-288.

Wilder, P. J., D. Kelly, K. Brigman, C. L. Peterson, T. Nowling, Q.-S. Gao, R. D. McComb, M. R. Capecchi and A. Rizzino (1997).  Inactivation of the FGF-4 gene in embryonic stem cells alters the growth and/or the survival of their early differentiated progeny.  Dev. Biol. 192:614-629.

Capecchi,  M. R. (1997).  The Making of a Scientist.  In Kyoto Prizes and Inamori Grants 1996.  Kyoto:  The Inamori  Foundation.

Hostikka, S. L. and M. R. Capecchi (1998).  The mouse Hoxc11 gene:  genomic structure and expression pattern.  Mech. Dev. 70:133-145.

Godwin, A. R. and M. R. Capecchi (1998).  Hoxc13 mutant mice lack external hair.  Genes Dev. 12:11-20.

Manley, N. R. and M. R. Capecchi (1998).  Hox group 3 paralogs regulate the development and migration of the thymus, thyroid and parathyroid glands.  Dev. Biol. 195:1-15.

Capecchi, M. R. (1998).  Gene targeting: an historical perspective.  In Novel Systems for the Study of Human Diseases--From Basic Research to Applications.  Pp. 49-54. OECD Proceedings.

Chen, F., J. Greer and M. R. Capecchi (1998).  Analysis of Hoxa7/Hoxb7 mutants suggests periodicity in the generation of the different sets of vertebrae.  Mech. Dev. 77:49-57.

Godwin, A. R.,  H. S. Stadler, K. Nakamura and M. R. Capecchi. (1998).  Detection of targeted GFP-Hox gene fusions during mouse embryogenesis.  Proc. Natl. Acad. Sci. USA 95:13042-13047.

Chen, F. and M. R. Capecchi.  (1999).  The paralogous mouse Hox genes, Hoxa9, Hoxb9 and Hoxd9, function together to control development of the mammary gland in response to pregnancy.  Proc. Natl. Acad. Sci. USA 96:541-546.

Schmidt, E. E., E. S. Hanson and M. R. Capecchi (1999). Sequence-independent assembly of spermatid mRNAs into mRNP particles.  Mol. Cell. Biol. 19:3904-3915.

Bunting, M., K. E. Bernstein, J. M. Greer, M. R. Capecchi and K. R. Thomas (1999).  Targeting genes for self-excision in the germline.  Genes Dev.13:1524-1528.

Barrow, J. R. and M. R. Capecchi (1999).  Compensatory defects associated with mutations in Hoxa1 restore normal palatogenesis to Hoxa2 mutants.  Development 126:5011-5026.

Rossel, M. and M. R. Capecchi (1999).  Mice mutant for both Hoxa1 and Hoxb1 show extensive remodeling of the hindbrain and defects in craniofacial development.  Development126:5027-5040.

Godwin, A. R. and M. R. Capecchi (1999).  Hair defects in Hoxc13 mutant mice.  J. Invest. Dermatol. Symp. Proc. 4:244-247.

Hashimoto, J., G. Murakami, M. H. Tsugane, O. Chisaka, M. R. Capecchi and T. Ogino (1999).  Lumbosacral plexus in Hoxa9 knockout mice with special reference to their nerve variations identified according to whether they were interphenotypic or intergenotypic differences.  Kaibogaku Zasshi 74:609-630.

Capecchi, M. R.  (2000).  Human germline gene therapy:  How and why.  In Engineering the Human Germline.  (G. Stock and J. Campbell, Eds.)  New York:  Oxford University Press, pp. 31-42.

Greer, J. M., J. Puetz, K. R. Thomas and M. R. Capecchi (2000).  Maintenance of functional equivalence during paralogous Hox gene evolution.  Nature 403:661-665.

Barrow, J. R., H. S. Stadler and M. R. Capecchi (2000).  Roles of Hoxa1 and Hoxa2 in patterning the early hindbrain of the mouse.  Development 127:933-944.

Moon, A. M., A. M. Boulet and M. R. Capecchi (2000).  Normal limb development in conditional mutants of Fgf4.  Development 127:989-996.

Capecchi, M. R. (2000).  How close are we to implementing gene targeting in animals other than the mouse?  Proc. Natl. Acad. Sci. USA 97:956-957.

Capecchi, M. R. (2000).  Choose your target.  Nature Genet.26:159-161.

Schmidt, E. E., D. S. Taylor, J. R. Prigge, S. Barnett and M. R. Capecchi (2000).  Illegitimate Cre-dependent chromosome rearrangements in transgenic mouse spermatids.  Proc. Natl. Acad. Sci. USA 97:13702-13707.

Gaufo, G. O., P. Flodby and M. R. Capecchi (2000).  Hoxb1 controls effectors of sonic hedgehog and Mash1 signaling pathways.  Development 127:5343-5354.

Moon, A. M. and M. R. Capecchi (2000).  Fgf8 is required for outgrowth and patterning of the limbs.  Nature Genet.26:455-459.

Cole, J., D. Ertoy, H. Lin, R. L. Sutliff, E. Ezan, T. T. Guyene, M. R. Capecchi, P. Corvol, and K. E. Bernstein (2000).  Mice deficient in angiotensin converting enzyme (ACE) have anemia due to a lack of angiotensin II facilitated erythropoiesis. J. Clin. Invest.106:1391-1398.

Manley, N. R., J. R. Barrow, T. Zhang and M. R. Capecchi (2001).  Hoxb2 and Hoxb4 act together to specify ventral body wall formation.  Dev. Biol.237:130-144.

Stadler, H. S., K. M. Higgins and M. R. Capecchi (2001). Loss of Eph-receptor expression correlates with loss of cell adhesion and chondrogenic capacity in Hoxa13mutant limbs.  Development 128:4177-4188.

Capecchi, M.R. (2001). Gene targeting: Altering the genome in mice.  Ergito.  http://www.ergito.com/main.jsp?bcs=EXP.3.4

Capecchi, M.R. (2001). Generating mice with targeted mutations.  Nature Med. 7:1086-1090.

Cole, J., D. L. Quach, K. Sundaram, P. Corvol, M. R. Capecchi and K. E. Bernstein (2002).  Mice lacking endothelial ACE have a normal blood pressure.  Circ. Res. 90:87-92.

Greer, J. M. and M. R. Capecchi (2002).  Hoxb8 is required for normal grooming behavior in the mouse.  Neuron 33:23-34.

Wellik, D. M., P. J. Hawkes and M. R. Capecchi (2002).  Hox11 paralogous genes are essential for metanephric kidney induction.  Genes Dev.16:1423-1432.

Hobbs, N. K., A. A. Bondareva, S. Barnett, M. R. Capecchi and E. E. Schmidt (2002).  Removing the vertebrate-specific TBP N-terminus disrupts placental b2m-dependent interactions with the maternal immune system.  Cell110:43-54.

Boulet, A. M. and M. R. Capecchi (2002).  Duplication of the Hoxd11gene causes alterations in the axial and appendicular skeleton of the mouse.  Dev. Biol.249:96-107.

Frank, D. U., L. K. Fotheringham, J. A. Brewer, L. J. Muglia, M. Tristani-Firouzi, M. R. Capecchi and A. M. Moon (2002).  An Fgf8 mouse mutant phenocopies human 22q11 deletion syndrome.  Development129:4591-4603.

Vorbach, C., A. Scriven and M. R. Capecchi (2002).  The housekeeping gene Xanthine Oxidoreductase is necessary for milk fat droplet enveloping and secretion: gene sharing in the lactating mammary gland. Genes Dev.16:3223-3235.

Barrow, J. R., K. R Thomas, O. Boussadia-Zahui, R. Moore, R. Kemler, M. R. Capecchi, and A. P. McMahon (2003). Ectodermal Wnt3/b-catenin signaling is required for the establishment and the maintenance of the apical ectodermal ridge.  Genes Dev.17:394-409.

Schmidt, E. E., A. A. Bondareva, J. R. Radke and M. R. Capecchi (2003).  Fundamental cellular processes do not require vertebrate-specific sequences within the TATA-binding protein.  J. Biol. Chem.278:6168-6174.

Economides, K. D., L. Zeltser and M. R. Capecchi (2003).  Hoxb13 mutations cause overgrowth of caudal spinal cord and tail vertebrae.  Dev. Biol.256:317-330.

Cole J., N. Khokhlova, R. L. Sutliff, J. W. Adams, K. M. Disher, H. Zhao, M. R. Capecchi, P. Corvol and K. E. Bernstein (2003).  Mice lacking endothelial angiotensin-converting enzyme (ACE):  normal blood pressure with elevated angiotensin II. Hypertension41:313-321.

Economides, K. R. and M. R. Capecchi (2003).  Hoxb13 is required for normal differentiation and secretory function of the ventral prostate.  Development130:2061-2069.

Arenkiel, B. R., G. O. Gaufo and M. R. Capecchi (2003).  Hoxb1 neural crest preferentially form glia of the PNS.  Dev. Dynamics227:379-386.

Wellik, D. M. and M. R. Capecchi (2003).  Hox10 and Hox11 genes are required to globally pattern the mammalian skeleton.  Science301:363-367.

Vorbach, C., R. Harrison and M. R. Capecchi (2003).  Xanthine oxidoreductase is central to the evolution and function of the innate immune system.  Trends Immunol.  29:512-517.

Gaufo, G. O., K. R. Thomas and M. R. Capecchi (2003).  Hox3 genes coordinate mechanisms of genetic suppression and activation in the generation of branchial and somatic motor neurons.  Development130:5191-5201.

Wong, K. H. H., H. D. Wintch and M. R. Capecchi (2004).  Hoxa11 regulates stromal cell death and proliferation during neonatal uterine development.  Molec. Endocrin.  18:184-193.

Boulet, A. M. and M. R. Capecchi (2004). Multiple roles of Hoxa11 and Hoxd11 in the formation of the mammalian forelimb zeugopod.  Development131:299-309.

Westerberg, R., P. Tvrdik, A. B. Unden, J. E. Mansson, L. Norlen, A. Jakobsson, W. H. Holleran, P. M. Elias, A. Asadi, P. Flodby, R. Toftgard, M. R. Capecchi and A. Jacobsson (2004). Role for ELOVL3 and fatty acid chain length in development of hair and skin function.  J. Biol. Chem. 279:5621-5629.

Gaufo, G.O., S. Wu and M. R. Capecchi (2004).  Contribution of Hox genes to the diversity of the hindbrain sensory system.  Development 131:1259-1266.

Fuchs, S., H. D. Xiao, J. W. Adams,  K. Frenzel, G. Keshelava ,  M. R. Capecchi , P.  Corvol and K. E. Bernstein (2004). Role of the N-terminal catalytic domain of ACE investigated by targeted inactivation in mice.  J. Biol. Chem. 279:15946-15953.

Arenkiel,  B. R., P. Tvrdik, G. O. Gaufo and M. R. Capecchi (2004).  Hoxb1 functions in both motoneurons and tissues of the periphery to establish and maintain the proper neuronal circuitry.  Genes Dev.18:1539-1552.

Boulet, A. M., A. M. Moon, B. R. Arenkiel and M. R. Capecchi (2004).  The roles of Fgf4 and Fgf8 in limb bud initiation and outgrowth.  Dev. Biol.273:361-372.

Xiao,  H. D., S. Fuchs, D. J. Campbell , W. Lewis, S. C. Dudley, Jr., V. S. Kasi, B. D. Hoit, G. T. Keshelava , H. Zhao, M. R. Capecchi and K. E. Bernstein (2004). Mice with cardiac restricted angiotensin converting enzyme (ACE) have atrial enlargement and sudden death.  Am. J. Path. 165:1019-1032.

Keller, C., M. S. Hansen, C. M. Coffin and M. R. Capecchi (2004).  Pax3:Fkhr interferes with embryonic Pax3 and Pax7 function:  implications for alveolar rhabdomyosarcoma cell of origin.  Genes Dev.  18:2608-2613.

Keller, C., B. R. Arenkiel, C. M. Coffin, N. El-Bardeesy, R. A.  DePinho and M. R. Capecchi (2004).  Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function.  Genes Dev.  18:2614-2626.